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Biological imaging

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Multiphoton microscopy (MPM) is a non-invasive, high-resolution imaging method for looking at thick biological tissues. We use a femtosecond laser to develop MPM systems which can acquire two-photon excited fluorescence (TPEF) and second harmonic generation (SHG) simultaneously. The MPM system is used to image cells and extracellular matrix in turbid tissues.
This project aims to develop micro-endoscopes for in vivo intra-luminal tissue imaging. The design will use state-of-the-art techniques such as photonic crystal fibers, micro-optics, and MEMS scanners. The micro-endoscopes will enable high resolution, multimodality imaging of subsurface structures and compositions of internal organs.
The goal of this project is to design and construct a portable and cost effective magnetic resonance imaging (MRI) instrument that is capable of resolving features at microscale to image flow fields of complex fluids in capillary tubes.
Schematics of MRI for Flow Visualization Instrument