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Deposition of particles from polydisperse suspensions in microfluidic systems

Publication Type:

Journal Article


Microfluidics and Nanofluidics, Volume 9, Issue 4-5, p.905-913 (2010)



Polymer microspheres can deposit successively in microfluidic channels until they block a flow passage, which then leads to device failure. This paper presents investigations of the effect of particle size distribution on the dynamics of channel blockage in microfluidic systems. The presented measurements and observations show that a low concentration of relatively large particles in a suspension has a major effect on the average time for a microchannel to be blocked by particles. Depending of on the size distribution of particles in a suspension microchannel blockage occurs through successive particle deposition, particle size exclusion, or through a combination of these effects.

Faculty Member(s): 
Research Area(s): 
Biomedical Engineering
Research Area(s): 
Sensors and Actuators