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Bio Sensor

Abstract

Due to the large surface-to-volume ratio of nanostructures, they are excellent candidates for ultra-high-sensitivity detection of chemicals and biological molecules. Our objective is the sensitive detection of RNA using such structures, with the ultimate goal of single-RNA detection.

Project Description

Abnormalities in RNA result in disease, thus RNA profiling is a powerful approach towards understanding and diagnosing disease. Due to the large surface-to-volume ratio of nanostructures, they are excellent candidates for ultra-high-sensitivity detection of chemicals and biological molecules. A variety of approaches can be used to make nanostructured sensors. For instance, the adsorption of a small number of molecules on a nanotube- or nanowire-based field-effect transistor can drastically alter its current-voltage chracteristics, enabling detection. Our objective is the sensitive detection of RNA using such structures, with the ultimate goal of single-RNA detection.

Faculty Supervisor(s)

    Alireza.Nojeh   

Researchers(s)

       

Research Area(s)