@article { Wang2013jbp, title = {A silicon photonic biosensor using phase-shifted Bragg gratings in slot waveguide}, journal = {Journal Biophotonics}, volume = {6}, year = {2013}, note = {This is the pre-peer reviewed version of the following article: Wang, X., Flueckiger, J., Schmidt, S., Grist, S., Fard, S. T., Kirk, J., Doerfler, M., Cheung, K. C., Ratner, D. M. and Chrostowski, L. (2013), A silicon photonic biosensor using phase-shifted Bragg gratings in slot waveguide. J. Biophoton.. doi: 10.1002/jbio.201300012, which has been published in final form at [http://onlinelibrary.wiley.com/doi/10.1002/jbio.201300012/abstract]. http://www.mina.ubc.ca/files/JBP-pre-peer-review.pdf }, month = {04/2013}, pages = {821--828}, abstract = {We present a novel silicon photonic biosensor using phase-shifted Bragg gratings in a slot waveguide. The optical field is concentrated inside the slot region, leading to efficient light-matter interaction. The Bragg gratings are formed with sidewall corrugations on the outside of the waveguide, and a phase shift is introduced to create a sharp resonant peak within the stop band. We experimentally demonstrate a high sensitivity of 340 nm/RIU measured in salt solutions and a high quality factor of 1.5 10^{4}, enabling a low intrinsic limit of detection of 3 10^{?4} RIU. Furthermore, the silicon device was fabricated by a CMOS foundry, facilitating high-volume and low-cost production. Finally, we demonstrate the device's ability to interrogate specific biomolecular interactions, resulting in the first of its kind label-free biosensor. ( 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) }, keywords = {biosensor, silicon photonics,slot waveguide, Bragg grating, microfluidics, limit of detection}, URL = {http://onlinelibrary.wiley.com/doi/10.1002/jbio.201300012/abstract}, author = {Xu Wang and Jonas Flueckiger and Shon Schmidt and Samantha Grist and Sahba Talebi Fard and James Kirk and Matt Doerfler and Karen C. Cheung and Daniel M. Ratner and Lukas Chrostowski} }