@inproceedings { Flueckiger2011b, title = {Label-Free Biosensing Using Cascaded Silicon-on-Insulator Micro-Racetrack Resonators Integrated With PDMS Microfluidic Channels}, journal = {The 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences}, year = {2011}, month = {10/2011}, address = {Seattle, Washington, USA}, abstract = {This paper demonstrates a label-free biosensing platform using Silicon-On-Insulator (SOI) micro-racetrack resonators, cascaded such that multiple measurements can be made using a single input and output waveguide and therefore a single detector. The devices are integrated with poly(dimethylsiloxane) microfluidic channels in order to characterize the devices? sensing properties. Both bulk refractive index sensing using glycerin/water solutions and clinically-relevant biosensing using Human Factor IX and its corresponding antibody are characterized. Bulk sensitivities of 40 nm/RIU are achieved, and the devices are able to sense both the protein attachment during functionalization and the protein-antibody binding reaction.}, author = {Jonas Flueckiger and Samantha M. Grist and Eric Ouellet and Lukas Chrostowski and Karen C. Cheung} }